Injectable suspensions
The impact of particle sizes and dissolution parameters can be discriminated for suspensions and emulsions using a flow-through cell dissolution system according to compendial methods described in United States Pharmacopeia <USP 711> and European Pharmacopoeia 2.9.3. When conducting bioequivalence studies of suspensions, SOTAX customers found Apparatus 4 as an ideal tool for product development and subsequentially applied the technique to all suspension development moving forward - overcoming challenges associated with low dose and small particles.
Quality control tests
SOTAX flow-through cell dissolution systems are routinely used to test injectable suspensions.